P 216 Calcium distribution in the human lens

P 216 Calcium distribution in the human lens

m To IIIthe absorption we&km a, expressed in cm.‘. of a 2940 nm infrared radiation through ndcmxctions of human and porcine lenses. m Human lens nuclei from extracapsulwly cataract pmcedures and porcine lens from freshly enucleakd porcine eyes were crycat in IO, 15 and 30 pm sccdons. The crymctions were placed on micmsopc slides and covered by cover slips, whose edgs were painted with unmloured...

Regional differences in functional receptor distribution and calcium mobilization in the intact human lens.

PURPOSE To investigate regional differences in Ca(2+) mobilization kinetics in the intact human lens produced by exposure to agonists of tyrosine-kinase and G-protein-coupled receptors and to characterize the major receptor subtypes involved in Ca(2+) signaling in the different regions. METHODS Whole human lenses were placed anterior side down in a plastic chamber and perifused with artificia...

P 219 Distribution of integrins in the rabbit lens epithelium

Purpose : Cell-~11 and cell-subsbatum interactions are mediated through different families of receptors in particular integrins. These cell receptors influence many physiological processes including cellular pmlifemtion and differentiation which are implicated in the secondzuy cataract development. The current study reports the distribution of the integrins expressed at the cell surface in a no...

Calcium activates SK channels in the intact human lens.

PURPOSE Apamin-sensitive, calcium-activated SK potassium channels have been implicated in schizophrenia and myotonic dystrophy (MD), and both conditions carry an increased risk of cataract. The presence and functional activity of SK channels were therefore investigated in the human lens. METHODS The expression of all three members of the SK channel family was quantified by PCR. Their function...

Expression and Distribution of Calcium-Binding Protein S100P in Human Placenta during Pregnancy